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Session Information

ENDO 2010 Annual Meeting - Includes 5 Complimentary Sessions

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CLINICAL - When & How To Use Vitamin D

Track : CLINICAL

Program Code: M41

Date: Monday, June 21, 2010

Time: 2:45 PM to 3:30 PM EST

Location: 28ABC

SPEAKER :

Daniel D. Bikle, MD,PHD, VAMC/Univ of California-San Francisco
Disclosure: Nothing to Disclose

Dr. Bikle is Professor of Medicine and Dermatology at the University of California, San Francisco and Staff Physician at the San Francisco Veterans Affairs Medical Center. He received his A.B. from Harvard, his M.D. and Ph.D from the University of Pennsylvania, and his residency training from the Peter Bent Brigham Hospital. His clinical interests are in the roles of vitamin D and PTH in regulating bone mineral metabolism, and the diseases of such that ensue with abnormalities in such regulation. His research is similarly focused on the hormonal regulation of calcium metabolism, and includes projects involving the classic target tissues of bone and intestine as well as non classic tissues including the skin. One project attempts to understand the molecular mechanisms by which 1,25(OH)2 D regulates intestinal calcium transport, in particular calcium transport across the brush border using animal models in which critical components of 1,25(OH)2 D signaling and the calcium transport process have been deleted in the intestine. His second project is evaluating the effects of parathyroid hormone and insulin like growth factor-1 on bone formation, with particular interest in the effects of mechanical loading on the anabolic actions of these hormones, examining at the molecular level the signaling pathways mediating these hormones as affected by loading. As for the intestine, he is using animal models in which IGF-I and its receptor have been conditionally deleted in bone for these studies. His third project is examining the mechanisms by which calcium and 1,25(OH)2 D regulate keratinocyte differentiation, focusing on the calcium receptor and the vitamin D receptor, and the signaling pathways and transcriptional events mediated by their activation, again using animal models lacking the calcium receptor and vitamin D receptor in the epidermis.

Audio Synchronized to PowerPoint

(Code: M41)

This session is a part of:

The COMPLETE Bundle: Full Regular ENDO Session Library + Career Development Resources + Thyroid Ultrasonography (Online Access & DVD-ROM)

Full Regular ENDO Session Library (Online Access & DVD-ROM)