The crossmatch is known as a way to help ensure compatibility of blood between a donor and its recipient. Crossmatch procedures must therefore be designed in a manner to provide the safest blood as quickly as possible. The advancements of laboratory information systems in transfusion services has lead to the emergence of computer crossmatches. It is now possible for blood banks to develop procedures which work with laboratory information systems to develop an electronic crossmatch that can replace the immediate spin crossmatch. The speaker will take a closer look at the needs of an adequate LIS to accomodate an electronic crossmatch and discuss how it meets the certifying bodies requirements for transfused blood. With this knowledge a standard operating procedure can be developed. Finally, the program will focus on the actual steps to take to implement an electronic crossmatch in your laboratory and describe the necessary elements that will be needed to document the validation of your system.