This session will consist of compelling examples of current practices and evolving therapies intended to restore sight in the case of degenerative disease or damage. Participants will be informed of state-of-the-art banking, processing and transplantation of corneal grafts. The program will proceed with a stimulating illustration of primary culture and transplantation of limbal epithelial cells to repair damaged corneas. The session will conclude with a discussion of a promising gene therapy to treat individuals with incurable inherited retinal disease. Each speaker will illustrate a successful bench-to-bedside story including a description of the disease, laboratory approach, regulatory hurdles and clinical results.