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Session Information
AABB Audioconference Series 2009
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Update on Allogeneic Hematopoietic Cell Transplantation
Track : CELLULAR THERAPIES
Program Code: 094580
Date: Wednesday, April 29, 2009
Time: 2:00 PM to 3:30 PM  EST
DIRECTOR :
Ginna Laport, MD, Associate Professor, Stanford University
MODERATOR :
Robert Negrin, MD, Director, Divison of Blood and Marrow Transplantation, Stanford Hospital & Clinics
SPEAKER (S):
Steven Devine, MD, Director, Blood and Marrow Transplant Program, The Ohio State University
Improving Stem Cell Mobilization by Targeting CXCR4
Ginna Laport, MD, Associate Professor, Stanford University
The Expanding Pool of Allogeneic Hematopoietic Stem Cells
Krishna Komanduri, M.D., Director, Adult Stem Cell Transplant Program, University of Miami Sylvester Cancer Center
Allogeneic stem cell transplantation: using cellular therapy to reduce GVHD
Description
The sources of allogeneic hematopoietic cells continues to grow. One speaker will discuss the data supporting the choice of either peripheral blood or marrow as an allogeneic stem cell source as well as alternative cell sources such as cord blood registries and haploidentical donors. With regards to the mobilization of allogeneic hematopoietic cell sources, G-CSF has been the standard for over a decade. But, the advent of newer agents such as the CXCR4 antagonist, AMD3100, may change the standards of both autologous and allogeneic hematopoietic cell collection. Finally, regulatory T cells are a subset of lymphocytes that are increasingly being studied in adoptive immunotherapy protocols. This distinctive T cell population may play a vital role in controlling graft vs host disease in the allogeneic transplant setting.

  • Discuss the expanding pool of hematopoietic cell sources.
  • Discuss the role and summarize the clinical aspects of cytokines and chemokines in the mobilization of allogeneic stem cells with an emphasis on AMD3100 and novel agents
  • Present the background information on the biology of regulatory T cells, procurement and expansion and their expanding role in the allogeneic hematopoietic cell setting.
  • Provide background information on the biology of stem cell trafficking and eggress.


CE CategoryCE Value
California Clinical Laboratory Personnel 1.5
California Nurse 1.8
Florida Laboratory Personnel 1.8
General Attendee 1.5
Physician 1.5
Please note: Continuing education (CE) credit is available for online offerings only. Individuals that purchase CD-ROMs will not receive CE credit for the programs they view.

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