Many gifted children experience asynchronous development in early childhood. Some developmental milestones are achieved early, while the attainment of other are delayed. Research findings stress the importance of early interventions, but determining when and how to intervene effectively can be difficult. Cognitive, physical, social, emotional, and speech and language development milestones can alert parents and educators when further assessments are necessary. Participants learn how to infuse the arts and combine effective gifted and special education interventions to develop 21st century skills in creativity, critical thinking, problem solving, collaboration, goal setting, and self-regulation to help children achieve their potential.