This study examined talent development using the Differentiated Model of Giftedness and Talent. Participants were five male science winners of the Davidson Fellowship, which recognizes students under the age of 18 who have completed a significant piece of original work in one of six fields: science, technology, mathematics, music, literature, or philosophy. Parents of four of the Fellows also participated in the multiple-case study, which used semi-structured phone interviews to gather data. The cross-case analysis of this multiple-case study revealed that the Fellows traveled multiple pathways to success, the positive catalysts protecting their efforts from negative catalysts.